Immunohistochemical studies on the functional role of neuropeptides and their receptors in the central regulation of food intake
Informations
- Funding country
Hungary- Acronym
- -
- URL
- -
- Start date
- 4/5/2006
- End date
- 12/31/2009
- Budget
- 48,785 EUR
Fundings
| Name | Role | Start | End | Amount |
|---|---|---|---|---|
| Thematic Programme | Grant | 4/5/2006 | 12/31/2009 | 48,785 EUR |
Abstract
Based on morphological and physiological studies, the central position of the hypothalamus in the food intake has been demonstrate. It is organized by long-loop mechanisms including humoral and neural inputs to the hypothalamus, obligatory processing in hypothalamic neuronal circuits, and descending commands through vagal and spinal neurons to the body. A number of various hormones, neuropeptides, cannabinoids and their receptors are involved in these regulatory mechanisms. Their actions and their expression in hypothalamic and extrahypothalamic neurons as well as their interconnections (pathways) will be investigated by using neuroanatomical (tract-tracing), neurochemical (light and electron microscopical immunohistochemistry, in situ hybridization histochemistry) and experimental surgical techniques.